A ligandable PNT domain establishes ERG as a directly targetable oncogenic driver in prostate cancer
Published: 2026-07-20 • Permanent link
Proceedings of the National Academy of Sciences, Volume 123, Issue 28, July 2026.
SignificanceTheTMPRSS2: ERGgene fusion is the most common oncogenic driver in prostate cancer, yet the ERG transcription factor has long been considered undruggable due to the ab...
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Why it matters: Proceedings of the National Academy of Sciences, Volume 123, Issue 28, July 2026. SignificanceTheTMPRSS2:ERGgene fusion is the most common oncogenic driver in prostate cancer, yet the ERG transcription factor has long been considered undru...
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